Cayman Chemical ChIcago Sky Blue 6B 250g
A dye and derivative of glutamate with diverse biological activities; inhibits glutamate uptake by rat brain synaptic vesicles (Ki = 0.19 µM) but not synaptosomes at 0.1 mM; an inhibitor of CaMKP and CaMKP-N (IC50s = 4.1 and 1 µM, respectively); selective for CaMKP and CaMKP-N over PP2C and calcineurin, which it inhibits by less than 10 and 20%, respectively, at 10 µM; an inhibitor of NTCP (IC50 = 7.1 µM); reduces HBV and HDV infection in HepaRG cells at 17 µM; inhibits inflammatory pain and thermal hyperalgesia in mice at 0.5 UG